I'm hoping somebody knows more about this --
My s10 classic, bios 94, seems to be saving something to the last sector of the hard disk.
If that data gets corrupted, the computer will not boot, even from a bootable usb device, as long as the drive is present.
If the last sector is restored or zeroed out it will boot.
This might be associated with hibernation. (I also discovered the Bios isn't happy if you hibernate, pull the drive, and then attempt to boot from a USB device).
If that is all that's going on the workaround is trivial - leave a little unallocated space at the end when you repartition.
That seems to have solved my problem.
