Well I can only confirm, that the S10e works fine here with 10.6.7. However there is one negative point about the S10(e): Both do only use the Atom N270 processor, so no EM64T (64-bit) support.
That's important because Apple may drops the 32-bit-support in their OS X Lion operating system (but so far nobody knows - the developer previews still run on 32-bit machines, but maybe that's going to be changed in the final version)
And that would mean, that the S10e probably wouldn't be able to run OS X Lion (if they really drop it)
Just wanted to add that